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Gd-DTPA Enhancement of CSF in Meningeal Carcinomatosis J Comput Assist Tomogr 17:940-944, Pui,M.H.W.,et al, 1993 See this aricle in Pubmed Article Abstract All four patients demonstrated CSF enhancement after Gd-DTPA administration,which increased on delayed imaging and was more apparent following subtraction.Three of the four patients died within 5 months of the MRI examination.CSF enhancement in uncommon,but when seen indicates massive tumor that coats the surface of the CNS.Detection of CNS enhancement may alter therapy;however,prognosis may be poor when CSF enhancement is present.Delayed imaging and subtraction may improve detection of CSF enhancement.

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